Association between Liver Function Indices and Cardiometabolic Risk Factors with Neck Circumference and Body Shape Index A in Patients with Type 2 Diabetes in the Educational-clinical Centers of Abadan University of Medical Sciences, Abadan, Iran, 20

Background and Objectives: Neck circumference and A body shape index are anthropometric indicators and the index of visceral obesity can predict initiation of type 2 diabetes mellitus. The aim of this study was to investigate associations between the biochemical indicators of liver function and cardiometabolic risk factors with the highlighted anthropometric indicators in patients with type 2 diabetes mellitus. Materials and Methods: This study was carried out on 297 male and female patients over 19 years old with type 2 diabetes in educational and therapeutic centers of Abadan University of Medical Sciences, Abadan, Iran, 2021. Circumference of the neck was measured using tape measure and body shape index A was assessed using mathematical formula. First, 5 ml of blood were collected from the patients to assess biochemical factors, including sugar profile, lipid profile and serum level of liver enzymes using enzymatic methods. Results: Pearson's correlation coefficient showed that neck circumference included direct significant associations with serum fasting blood sugar (r = 0.332 and p < 0.001), triglycerides (r = 0.159 and P = 0.006) and total cholesterol (r = 0.203 and p < 0.001) levels. Neck circumference included direct significant associations only with fasting blood sugar (r = 0.45 and p < 0.001) in people with normal body mass index. In all type 2 diabetes patients, natural significant associations were seen between A body shape index and serum aspartate transaminase levels (r = 0.129 and p = 0.026). In obese patients, A body shape index included direct significant associations only with HbA1C (r = 0.28 and p = 0.009). Conclusion: These findings have shown that neck circumference and A body shape index are predictors of cardiometabolic and liver risks in patients with type 2 diabetes mellitus.